The Strength trial is a phase III, multi-center study enrolling patients with high triglyceride levels and low HDL cholesterol levels who have or are at risk for future cardiovascular events. The investigational product, an oral Omega-3 (study drug) or placebo (Corn Oil), will be added to your current daily statin medication.
About 13,000 patients at approximately 600 sites worldwide will take part in this 3-5 year study. There are potentially 13 visits to the study site. Visit procedures include counseling for the TLC (Therapeutic Lifestyle Changes) diet, physical examinations, vital signs and ECGs.
All study procedures and medication is provided to you at no cost and financial compensated is available for your time and travel to the study site.
All information you provide is stored in a secure site, and cannot be released to any third party without your written and signed authorization.
Everyone has heard about the connection between high levels of cholesterol and coronary heart disease, which is blamed for about 500,000 deaths every year in the U.S.
You’re probably concerned about your cholesterol level, but if you’re like most, you find the language about cholesterol and other lipids — fatty substances in the body — confusing.
Your total cholesterol level provides a rough estimate of heart disease risk.
Cholesterol is transported through the bloodstream by lipoproteins (lipid plus protein) carriers. Total cholesterol level includes the amount of cholesterol carried by HDL (high-density lipoprotein) and LDL (low-density lipoprotein), as well as a small amount carried by very-low-density lipoprotein. This measurement, however, does not give a specific value for each lipoprotein. The total cholesterol test is used to screen for heart disease risk or to monitor general progress in those on a special diet or medication for high cholesterol.
HDL-C is known as the “good” cholesterol because higher HDL, levels are generally associated with lower risk for heart disease. HDL-C is believed to take excess cholesterol away from coronary arteries. The more HDL cholesterol you have, the better.
LDL-C is known as the “bad” cholesterol because too much LDL in the blood is associated with blockage of the arteries in the heart. LDL cholesterol is calculated in those who have a high total cholesterol level or other risk factors for heart disease.
Triglyceride is a lipid that helps store fat in the body. High glyceride levels can cause inflammation of the pancreas, and elevated levels of triglyceride may play a role in heart disease risk
You can take action to improve your lipid profile to help reduce your risk of heart disease: Stop smoking, change the way you eat, lose weight if necessary and start exercising.